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New treatment for premature ejaculation…

November 23, 2009

Soon, a spray to prevent premature ejaculation

An experimental spray, used just five minutes before sexual intercourse, has been found to effectively delay premature ejaculation in men, say

Couple

Soon, a spray that can prevent premature ejaculation (Getty Images)

researchers.

The spray called PSD502 includes two drugs lidocaine and prilocaine.



The study showed that men treated with PSD502 were able to delay ejaculation up to five times longer than those who used placebo.



It works selectively on non-keratinized skin on the glans penis (head of the penis).

The patients and partners in both trials reported significant improvements in sexual satisfaction, and the drug was well tolerated.



"Premature ejaculation can have a powerful negative impact on the emotional and sexual lives of men and their partners," said Professor Stanley E. Althof, PhD, Centre for Marital and Sexual Health of South Florida, West Palm Beach, Florida.



"Recently, the international sexual health community agreed that PE should be defined as ejaculation occurring within approximately one minute of penetration that causes the patient distress.



“Now we need to work to develop treatments, and these encouraging results with PSD502 seem to be a step in the right direction," Althofa added.



"We are excited that results from two pivotal studies have shown that PSD502 was effective for men with PE, and we look forward to the opportunity to help patients who have had no real options to date," said Patrick Fourteau, Chief Executive Officer of Sciele Pharma, Inc.



The study was presented at the annual meeting of the Sexual Medicine Society of North America (SMSNA), Inc. in


decisions…decisions..which Erectile Dysfunction drug is right for you?

October 12, 2009

How Do You Choose Right Erection Drug?

Viagra, Cialis, Levitra Have Similar Effects

Robert W. McDonald, Contriubting writer

 

Erectile dysfunction is the inability to achieve or to maintain an erection for a period of time sufficient to complete sexual intercourse. Although the available data regarding the number of men per year seeking treatment of ED varies depending on the data's source, ED is estimated to be present in some 5 percent of men under the age of 50 and in up to 25 percent of those over the age of 60, according to the American Journal of Science.

 

Several medical conditions — including high blood pressure, diabetes and high cholesterol — are known to be associated with ED. Most of those problems interfere with blood flow in the body's smaller arteries.

 

Many men who report sexual problems also smoke or use alcohol, and they are often present in those on certain high blood pressure or antidepressant medications. ED is also frequently seen following surgery on the prostate gland.

 

Three drugs are currently available for the treatment of ED, and all three belong to a class of drugs known as PDE-5 inhibitors. They exert their effects by causing a temporary buildup in a substance called nitric oxide which, in turn, causes the muscular walls of the small arteries in the penis to relax. That increases blood flow during sexual arousal.

 

Cialis, formally known as tadalafil, is by far the most popular ED medication. In 2008, it was responsible for 55 to 60 percent of the total worldwide sales of $2.1 billion for all ED drugs. Cialis' gained popularity because, unlike competitors Viagra and Levitra, it is the only ED medication that is approved for daily use, and its effects have been reported to last for as long as thirty-six hours.

 

Many men say that being able to take Cialis on a daily basis is the primary reason for selecting it over other medications.

 

Viagra, sildenafil, was the first medication proven to be effective in the treatment of ED. Viagra is usually taken one hour prior to the anticipated start of intercourse, and its effects usually last for some four to six hours. Viagra accounts for 20 to 25 percent of worldwide sales.

 

Levitra, vardenafil, also holds a 20 to 25 percent share of the worldwide market. Levitra is generally taken one hour ahead of time, and its duration of effect is the same as that found in Viagra. As with Viagra, Levitra is not recommended for routine daily use. At the retail level, Levitra is becoming more popular because it is generally about 10 to 15 percent cheaper than Viagra.

 

All three medications are known to cause some unpleasant, and even potentially dangerous, side effects. Among the most common are sudden decreases in blood pressure, visual disturbances and a ringing in the ears. More serious conditions include chest pain and an erection lasting beyond four hours. Each of these conditions must be treated on an emergency basis.

 

ED can be treated with several medications but, as with any other medical condition, using any ED drug should only be considered after discussing the advantages and potential disadvantages of each drug with a physician.


Looks like a new treatment for erectile dysfunction is on it's way….

September 19, 2009

'Rub-on Viagra' in development

A rub-on cream potentially as effective as Viagra but without any side effects is being developed by scientists.

 By Kate Devlin, Medical Correspondent
Published: 7:50AM BST 19 Sep 2009
A rub-on cream potentially as effective as Viagra but without any side effects is being developed by scientists.

Viagra could soon be available in a cream Photo: AFP/GETTY

The development could help millions of men every year.

Current erectile dysfunction drugs, called phosphodiesterase type 5 (PDE5) inhibitors, can cause side effects, ranging from headaches and vision problems to more serious complications.  

Men who have suffered a heart attack or a stroke are warned to be cautious when they take the medication, while an estimated one in three men find that the drugs do not work.

Doctors have now developed a new way of minimising side effects by delivering drugs directly to the affected area using tiny particles, smaller than the size of pollen grains.

Tests on rats have shown that the drugs are effective in nine out of 10 cases.

The researchers behind the breakthrough now say that they plan to test the mediation on humans, but warn it could be another 10 years before the product is on the market.

The team, at Albert Einstein College of Medicine of Yeshiva University, New York, said that other attempts at administering drugs through the skin had not been very successful.

Kelvin P. Davies, associate professor of urology and one of the co-authors of the study, added: "The response time to the nanoparticles was very short, just a few minutes, which is basically what people want in an Erectile Dysfunction medication.

"In both rats and humans, it can take 30 minutes to one hour for oral ED medications to take effect."

The findings were published online in the Journal of Sexual Medicine


Erectile Dysfunction….

August 8, 2009

Here is a great personal account from a woman who's husband suffered with Erectile Dysfunction

When Erectile Dysfunction Hits Home

Or, how NOT to turn your man into a meat dildo…

More Than a Little Blue Pill

The Mayo Clinic describes erectile dysfunction as “the inability to obtain an adequate erection for satisfactory sexual activity.” The cause may be physical or psychological. These men cannot achieve an erection without medical treatment. There are many online sources available for couples seeking help with erectile dysfunction, including the Mayo Clinic, The National Institutes for Health, and the American Medical Association. Men and their partners may also find erectile dysfunction support groups on the web or in their communities.

Sex Minus the Hard-On

We needed to shift focus from his penis to the entire act of sex itself. During one conversation about our sex life, Bill began to detail some of the things we’d done when we made love. To our amazement, we brought each other to orgasm without him having an erection. It was a light-bulb moment.

Since Bill no longer could no longer get it up, we had to learn to look at sexual stimulation beyond penetration. There’s no question that a penis can be very satisfying. The length and breadth of a hard dick can stimulate areas that are out of finger reach, but you really can do quite a lot with your fingers and tongue. Simple erotic touching to create extended foreplay can drive your partner wild.

Sometimes people take their bodies for granted. One way for couples to reacquaint themselves with their own bodies and the bodies of their lovers is to give each other a massage. Scented oils, such as peppermint, orange and grapefruit are invigorating and enhance physical pleasure. Give each other oral sex. Scratch one another’s backs and heads. Masturbate each other. Take things gradually. Don’t rush. There are countless possibilities for great sex without intercourse.

Instead of using a meat dildo, how about trying an interactive dildo (or two)? With a dildo in hand and you between your partner’s legs, you have complete control and have full “situational awareness” of what you are doing. If you like, you can introduce an anal sex toy to the party, to bring a little extra oomph to your sex play.

Prioritize Your Pleasure

When lovers are already communicating well, good sex follows. Some men and women focus too much on the goal—the orgasm. They don’t take time to enjoy one another’s bodies as they make love. Learn to enjoy giving pleasure to your lover. One of life’s biggest turn-ons is seeing your lover aroused. As you explore your lover’s body to learn new ways to arouse him or her, you too will become aroused.

Be very aware of the here and now. Don’t allow your mind to become distracted by job woes, car problems, the phone ringing, the cats hissing at each other, or other stressors. Banish such erotic-killing thoughts from your mind, and focus on your own body’s sensations as well as your lover’s.

Sometimes you have to plan for sex. Pack up the kids with the grandparents for the evening. Rent a room at a fancy hotel—preferably one with a spa—and spend a sexy evening or (better yet) weekend away from home. Buy some sex toys and plan an evening at home with your fun, new gadgets. My husband and I love foot massages, and we use massage candles and massage oils to tend to each other’s feet while watching endless reruns of Ramsey’s Kitchen Nightmares and Law & Order.

There are numerous possibilities for couples to have great sex that far outnumber mere penetration. While Bill and I no longer engage in conventional intercourse, we enjoy each other very much. I’ve learned to use clitoral vibrators to achieve orgasm without penetration, but when I do want something inside me, we use some of my favorite toys, such as a rabbit or thrusting vibrator. The trick is to simply enjoy what you have together. Once you get used to the idea of sensuality as a normal and enjoyable part of everyday life, you will find that you appreciate sensations that are not necessarily connected to the sex act—and as a result, your sex life will be greatly improved.


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